Firefly: The Game by Galeforce Nine

Playing Firefly feels a great deal like you'd imagine being in the 'verse with Mal and the crew would - resources are only scarce when you need them, money comes and goes freely, and the good luck to avoid crime lords, Reavers, and the Alliance lends a great deal to your prospects for survival. 

Before I begin, a short synopsis: this is a good game that becomes a VERY entertaining one if you're a big fan of Joss Whedon's incredible and tragically short-lived show.